The presence of corticosteroid residues was assessed in urine and liver samples from livestock of Sicily. A total of 630 bovine samples were collected from farms and slaughterhouses. The samples were analysed using solid-phase extraction (SPE) coupled with ultra-performance liquid chromatography tandem mass spectrometry (UHPLC–MS/MS). All the corticosteroids found were under the maximum residue limit imposed by Commission Regulation (EC) 37/2010. About 4% of liver samples showed dexamethasone levels above the limit of detection (LOD), with a mean of 1.5 ± 0.2 µg kg⁻¹. Betamethasone was found only in seven liver samples, with a mean of 1.6 ± 0.1 µg kg⁻¹. Furthermore, prednisolone and prednisone were found only in urine and liver samples from slaughterhouse, probably related to the high rate of stress for bovines. These results suggest good control practices adopted by Sicilian farms, able to ensure the quality of food products.

在西西里岛牲畜的尿液和肝样品中评估了皮质类固醇残留的存在。从农场和屠宰场总共收集了630个牛样品。使用固相萃取（SPE）结合超高效液相色谱串联质谱（UHPLC–MS / MS）对样品进行分析。发现的所有皮质类固醇均在欧盟法规（EC）37/2010规定的最大残留限量之内。约4％的肝样品显示地塞米松水平高于检测限（LOD），平均值为1.5±0.2 µg kg ^-1。仅在七个肝脏样品中发现倍他米松，平均含量为1.6±0.1 µg kg ^-1。此外，泼尼松龙和泼尼松仅在屠宰场的尿液和肝脏样品中发现，可能与牛的高应激率有关。这些结果表明西西里农场采用了良好的控制措施，能够确保食品的质量。