The aim of this study was to assess the washout rate (WOR) for thallium-201-chloride single-photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI) using cadmium zinc telluride detectors for SPECT (CZT SPECT) versus conventional Anger-type SPECT (conventional SPECT). A total of 52 Japanese patients were examined using CZT SPECT and conventional SPECT, and the global WORs were compared. Additionally, the MPI WORs were compared for patients with a normal MPI versus those in whom MPI reflected the patients' multivessel disease (MVD) MPI. Washout rates were similar when approximated by CZT SPECT versus conventional SPECT 12.59 ± 2.26%/h vs 12.57 ± 2.27%/h ( P = .997), respectively. The WOR values for CZT SPECT versus conventional SPECT were 13.42%/h (1.53%/h) vs 13.93%/h (1.24%/h) ( P = .337), respectively, for 7 normal MPI patients, and 10.64 ± 2.20%/h vs 10.84 ± 2.26%/h ( P = .848), respectively, for 7 MVD-MPI patients. The WOR values for normal MPI versus MVD-MPI patients for CZT SPECT were 13.42 ± 1.53%/h vs 10.64 ± 2.20%/h ( P = .025), respectively. Thallium-201-chloride WOR values obtained with high-efficiency CZT SPECT, which enabled significantly reduced imaging times and use of a low-dose protocol, were similar to those obtained with conventional SPECT.

中文翻译：

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使用碲化锌锌探测器对T 201单光子发射计算机断层扫描心肌灌注显像的洗脱率分析的探索性研究。

这项研究的目的是评估使用201碲化镉锌探测器（CZT SPECT）与传统的Anger-CS相比，使用201氯化chlor单光子发射计算机断层扫描（SPECT）心肌灌注成像（MPI）的洗脱率（WOR）。类型SPECT（常规SPECT）。使用CZT SPECT和常规SPECT对总共52名日本患者进行了检查，并比较了总体WOR。此外，比较了MPI正常的患者与MPI反映患者多血管疾病（MVD）MPI的患者的MPI WOR。当用CZT SPECT估算与传统SPECT分别为12.59±2.26％/ h和12.57±2.27％/ h时，洗脱速率相似（P = .997）。CZT SPECT与传统SPECT的WOR值分别为13.42％/ h（1.53％/ h）和13.93％/ h（1.24％/ h）（P = .337），7例正常MPI患者分别为10.64±2.20％/ h和10.84±2.26％/ h（P = .848）（7例MVD-MPI患者）。CZT SPECT的正常MPI与MVD-MPI患者的WOR值分别为13.42±1.53％/ h和10.64±2.20％/ h（P = .025）。通过高效CZT SPECT获得的201氯化物WOR值与传统SPECT相似，其显着减少了成像时间并使用了低剂量方案。