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A model of quantitative traits under frequency-dependent balancing selection.
Proceedings of the Royal Society B: Biological Sciences ( IF 3.8 ) Pub Date : 1990-05-22 , DOI: 10.1098/rspb.1990.0024
G S Mani 1 , B C Clarke , P R Shelton
Affiliation  

We describe a computer model that stimulates a combination of stabilizing and frequency-dependent selection acting on a quantitative character determined by several loci. The results correspond to many features of natural variations at both the phenotypic and genotypic levels. The model is robust, and its results are not strongly dependent either on the nature and shape of the function describing the stabilizing selection, or on the precise form of frequency dependence, except near the extrema. It suggests a mechanism for the maintenance of large amounts of variability, and shows a relation between population size and heterozygosity roughly corresponding to that found in nature. In this respect it is unlike the purely neutral model.

中文翻译:

基于频率的平衡选择下的数量性状模型。

我们描述了一种计算机模型,该模型可刺激稳定化和频率依赖性选择的组合,作用于由多个基因座确定的定量特征。结果对应于表型和基因型水平的自然变异的许多特征。该模型具有鲁棒性,除极值附近外,其结果均不强烈依赖于描述稳定选择的函数的性质和形状,也不依赖于频率依赖的精确形式。它提出了一种维持大量变异性的机制,并显示了种群大小与杂合性之间的关系,大致与自然界中的关系相对应。在这方面,它不同于纯中立模型。
更新日期:2019-11-01
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