The recent rapid increase in interest in tomographic imaging of small animals and of human (and large animal) organ biopsies is driven largely by drug discovery, cancer detection/monitoring, phenotype identification and/or characterization, and development of disease detection methods and monitoring efficacies of drugs in disease treatment. In biomedical applications, micro-computed tomography (CT) scanners can function as scaled-down (i.e., mini) clinical CT scanners that provide a three-dimensional (3-D) image of most, if not the entire, torso of a mouse at image resolution (50-100 microm) scaled proportional to that of a human CT image. Micro-CT scanners, on the other hand, image specimens the size of intact rodent organs at spatial resolutions from cellular (20 microm) down to subcellular dimensions (e.g., 1 microm) and fill the resolution-hiatus between microscope imaging, which resolves individual cells in thin sections of tissue, and mini-CT imaging of intact volumes.

中文翻译：

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微型计算机断层扫描技术的现状和发展。

最近对小型动物和人类（和大型动物）器官活检的断层成像的兴趣迅速增加，其主要原因是药物发现，癌症检测/监测，表型鉴定和/或表征以及疾病检测方法和监测功效的发展疾病治疗药物。在生物医学应用中，微型计算机断层扫描（CT）扫描器可以用作按比例缩小（即微型）的临床CT扫描器，可提供鼠标大部分（如果不是整个）躯干的三维（3-D）图像图像分辨率（50-100微米）的比例与人类CT图像的比例成比例。另一方面，Micro-CT扫描仪则以空间分辨率从细胞（20 microm）到亚细胞尺寸（例如，