Few treatment options are available for patients suffering from diseased and injured organs because of a severe shortage of donor organs available for transplantation. Therapeutic cloning, where the nucleus from a donor cell is transferred into an enucleated oocyte in order to extract pluripotent embryonic stem cells, offers a potentially limitless source of cells for replacement therapy. Scientists in the field of tissue engineering apply the principles of cell transplantation, material science, and engineering to construct biological substitutes that will restore and maintain normal function in diseased and injured tissues. The present chapter reviews recent advances that have occurred in therapeutic cloning and tissue engineering and describes applications of these new technologies that may offer novel therapies for patients with end-stage organ failure.

中文翻译：

---

组织工程在治疗性克隆中的应用。

由于可移植的供体器官严重短缺，很少有治疗方法可用于患病和受伤器官的患者。治疗性克隆将供体细胞的核转移到去核的卵母细胞中，以提取多能胚胎干细胞，为替代治疗提供了无限可能的细胞来源。组织工程领域的科学家运用细胞移植，材料科学和工程学的原理来构建生物替代品，这些替代品将恢复并维持患病和受伤组织的正常功能。