FtsZ is a prokaryotic tubulin homolog that assembles into a ring at the future site of cell division. The resulting "Z ring" forms the framework for the division apparatus, and its assembly is regulated throughout the bacterial cell cycle. A highly dynamic structure, the Z ring exhibits continual subunit turnover and the ability to rapidly assemble, disassemble, and, under certain circumstances, relocalize. These in vivo properties are ultimately due to FtsZ's capacity for guanosine triphosphate (GTP)-dependent, reversible polymerization. FtsZ polymer stability appears to be fine-tuned such that subtle changes in its assembly kinetics result in large changes in the Z ring structure. Thus, regulatory proteins that modulate FtsZ's assembly dynamics can cause the ring to rapidly remodel in response to developmental and environmental cues.

中文翻译：

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细菌细胞分裂蛋白FTSZ的组装动力学：处于稳定性边缘。

FtsZ是一种原核微管蛋白同源物，在未来的细胞分裂位点组装成一个环。所得的“ Z环”形成了分裂装置的框架，并且其组装在整个细菌细胞周期中受到调节。Z环是一种高度动态的结构，具有连续的亚基周转率，并具有快速组装，拆卸和在某些情况下重新定位的能力。这些体内特性最终归因于FtsZ依赖于鸟苷三磷酸（GTP）的可逆聚合的能力。FtsZ聚合物的稳定性似乎已经过微调，以至于其组装动力学的细微变化导致Z环结构发生了巨大变化。因此，调节FtsZ'的调节蛋白