Bone and the immune system are both complex tissues that respectively regulate the skeleton and the body's response to invading pathogens. It has now become clear that these organ systems often interact in their function. This is particularly true for the development of immune cells in the bone marrow and for the function of bone cells in health and disease. Because these two disciplines developed independently, investigators in each don't always fully appreciate the significance that the other system has on the function of the tissue they are studying. This review is meant to provide a broad overview of the many ways that bone and immune cells interact so that a better understanding of the role that each plays in the development and function of the other can develop. It is hoped that an appreciation of the interactions of these two organ systems will lead to better therapeutics for diseases that affect either or both.

中文翻译：

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骨免疫学：骨骼和免疫系统的相互作用。


骨骼和免疫系统都是复杂的组织，分别调节骨骼和身体对入侵病原体的反应。现在已经清楚的是，这些器官系统经常在其功能上相互作用。对于骨髓中免疫细胞的发育以及骨细胞在健康和疾病中的功能来说尤其如此。由于这两个学科是独立发展的，因此每个学科的研究人员并不总是充分认识到另一个系统对他们所研究的组织功能的重要性。本综述旨在对骨骼和免疫细胞相互作用的多种方式提供广泛的概述，以便更好地了解每种细胞在另一种细胞的发育和功能发展中所发挥的作用。希望对这两个器官系统相互作用的认识能够为影响其中一个或两者的疾病提供更好的治疗方法。