The last decade has witnessed an exponential increase in interest in one of the great mysteries of nerve cell biology: Specifically, how do neurons know where to place the ion channels that control their excitability? Many of the most important insights have been gleaned from studies on the voltage-gated potassium channels (Kvs) which underlie the shape, duration and frequency of action potentials. In this review, we gather recent evidence on the expression, trafficking and maintenance mechanisms which control the surface density of Kvs in different subcellular compartments of neurons and how these may be regulated to control cell excitability.

中文翻译：

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电压门控钾通道在神经元中的表面表达和分布（综述）。

在过去的十年中，人们对神经细胞生物学的一个重大谜团之一的兴趣呈指数增长：具体来说，神经元如何知道将控制其兴奋性的离子通道放置在何处？通过对电压门控钾离子通道（Kvs）的研究，已经获得了许多最重要的见解，这些通道是动作电位的形状，持续时间和频率的基础。在这篇综述中，我们收集了有关表达，运输和维持机制的最新证据，这些机制控制着Kvs在神经元的不同亚细胞区室中的表面密度，以及如何调节它们以控制细胞的兴奋性。