Terry Beveridge's enthusiasm about the ingenuity of microorganisms has stimulated many new avenues of microbial research. One example where Terry's observations helped direct the scientific process was in the analysis of the draft genome of the thermoacidophilic archaeum, Aciduliprofundum boonei. This deep-sea vent heterotroph ferments peptides as its primary metabolic pathway, using numerous enzymes encoding for proteolytic or peptidolytic activities. An almost complete modified Embden-Meyerhof-Parnas pathway operates in the gluconeogenic direction. Terry was particularly intrigued by the S-layer and flagellum of A. boonei. Although only putative genes for the S-layer protein could be identified, several genes encoding for glycosyl transferases were located in the draft genome that could glycosylate the S-layer proteins and protect the proteins from the acidic environment. Furthermore, A. boonei possesses a unique organization to its flagellum genes and may represent a third organizational type within the Archaea.

中文翻译：

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电子显微镜遇到不寻常的嗜热菌有助于直接对嗜酸杆菌（Aciduliprofundum boonei）进行基因组分析。

特里·贝弗里奇（Terry Beveridge）对微生物创造力的热情刺激了微生物研究的许多新途径。特里的观察帮助指导科学过程的一个例子是对嗜热嗜酸古菌酸性嗜酸菌的基因组草图的分析。这种深海口异养菌利用许多编码蛋白水解或肽水解活性的酶，将肽作为其主要的代谢途径进行发酵。几乎完整的修饰的Embden-Meyerhof-Parnas途径在糖异生方向上起作用。特里对A. boonei的S层和鞭毛特别感兴趣。尽管只能识别出S层蛋白的推定基因，编码糖基转移酶的几个基因位于基因组草图中，可以使S层蛋白质糖基化并保护蛋白质免受酸性环境的侵害。此外，布氏曲霉对其鞭毛基因具有独特的组织，并且可能代表古细菌中的第三种组织类型。