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Biosynthesis of the iron-molybdenum cofactor of nitrogenase.
Annual Review of Microbiology ( IF 8.5 ) Pub Date : 2008-04-24 , DOI: 10.1146/annurev.micro.62.081307.162737
Luis M Rubio 1 , Paul W Ludden
Affiliation  

The iron-molybdenum cofactor (FeMo-co), located at the active site of the molybdenum nitrogenase, is one of the most complex metal cofactors known to date. During the past several years, an intensive effort has been made to purify the proteins involved in FeMo-co synthesis and incorporation into nitrogenase. This effort is starting to provide insights into the structures of the FeMo-co biosynthetic intermediates and into the biochemical details of FeMo-co synthesis.

中文翻译:

固氮酶的铁钼辅因子的生物合成。

位于钼固氮酶活性位点的铁-钼辅因子(FeMo-co)是迄今为止已知的最复杂的金属辅因子之一。在过去的几年中,已经进行了大量的工作以纯化参与FeMo-co合成和掺入固氮酶的蛋白质。这项工作开始提供有关FeMo-co生物合成中间体的结构以及FeMo-co合成的生化细节的见识。
更新日期:2019-11-01
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