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Place cells, grid cells, and the brain's spatial representation system.
Annual Review of Neuroscience ( IF 12.1 ) Pub Date : 2008-02-21 , DOI: 10.1146/annurev.neuro.31.061307.090723
Edvard I Moser 1 , Emilio Kropff , May-Britt Moser
Affiliation  

More than three decades of research have demonstrated a role for hippocampal place cells in representation of the spatial environment in the brain. New studies have shown that place cells are part of a broader circuit for dynamic representation of self-location. A key component of this network is the entorhinal grid cells, which, by virtue of their tessellating firing fields, may provide the elements of a path integration-based neural map. Here we review how place cells and grid cells may form the basis for quantitative spatiotemporal representation of places, routes, and associated experiences during behavior and in memory. Because these cell types have some of the most conspicuous behavioral correlates among neurons in nonsensory cortical systems, and because their spatial firing structure reflects computations internally in the system, studies of entorhinal-hippocampal representations may offer considerable insight into general principles of cortical network dynamics.

中文翻译:

放置细胞,网格细胞和大脑的空间表示系统。

超过三十年的研究表明,海马位置细胞在代表大脑空间环境中起着重要作用。新的研究表明,位置单元是用于自我定位动态表示的更广泛电路的一部分。该网络的关键组成部分是内嗅网格单元,其通过细分的发射场可以提供基于路径集成的神经图的元素。在这里,我们回顾了位置单元格和网格单元格如何构成行为,记忆中位置,路线和相关体验的定量时空表示的基础。由于这些细胞类型在非感觉皮层系统的神经元之间具有某些最明显的行为相关性,并且由于它们的空间触发结构反映了系统内部的计算,
更新日期:2019-11-01
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