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Mechanisms of sperm chemotaxis.
Annual Review of Physiology ( IF 15.7 ) Pub Date : 2007-11-09 , DOI: 10.1146/annurev.physiol.70.113006.100654
U Benjamin Kaupp 1 , Nachiket D Kashikar , Ingo Weyand
Affiliation  

Sperm are attracted by chemical factors that are released by the egg-a process called chemotaxis. Most of our knowledge on sperm chemotaxis originates from the study of marine invertebrates. In recent years, the main features of the chemotactic signaling pathway and the swimming behavior evoked by chemoattractants have been elucidated in sea urchins. In contrast, our understanding of mammalian sperm chemotaxis is still rudimentary and subject to an ongoing debate. In this review, we raise new questions and discuss current concepts of sperm chemotaxis. Finally, we highlight commonalities and differences of sensory signaling in sperm, photoreceptors, and olfactory neurons.

中文翻译:

精子趋化机制。

精子被卵所释放的化学因子所吸引,这一过程称为趋化性。我们对精子趋化性的大多数了解都来自对海洋无脊椎动物的研究。近年来,在海胆中已经阐明了趋化信号传导途径的主要特征和由化学引诱剂引起的游泳行为。相比之下,我们对哺乳动物精子趋化性的理解仍然是基本的,并且仍在进行中。在这篇综述中,我们提出了新的问题,并讨论了当前精子趋化性的概念。最后,我们强调了精子,感光细胞和嗅觉神经元中感觉信号的共性和差异。
更新日期:2019-11-01
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