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The cognitive neuroscience of schizophrenia.
Annual Review of Clinical Psychology ( IF 17.8 ) Pub Date : 2007-08-25 , DOI: 10.1146/annurev.clinpsy.1.102803.143959
Deanna M Barch 1
Affiliation  

Individuals with schizophrenia experience a range of cognitive deficits and associated dysfunctions in the neural systems that support cognitive processes. This chapter reviews the literature on disturbances in working memory, executive control, and episodic memory in schizophrenia. Advances in basic cognitive neuroscience are described to help explain the cognitive neuroscience of schizophrenia. For working memory in schizophrenia, evidence is reviewed regarding deficits in the verbal (phonological loop) and nonverbal (visual-spatial scratch pad) buffer systems as well as in the central executive function. In the domain of episodic memory, evidence is reviewed for deficits in recollection versus familiarity processes in episodic memory. Also discussed are conceptual issues and potential confounds relevant to understanding the cognitive neuroscience of schizophrenia, including the role that cognitive deficits play in the developmental course of schizophrenia, relationships to specific symptom domains, behavioral performance confounds, and medication influences on behavioral performance and brain function.

中文翻译:

精神分裂症的认知神经科学。

精神分裂症患者在支持认知过程的神经系统中会遇到一系列认知缺陷和相关功能障碍。本章回顾了有关精神分裂症中工作记忆,执行控制和情节性记忆障碍的文献。描述了基本认知神经科学的进展,以帮助解释精神分裂症的认知神经科学。对于精神分裂症的工作记忆,需要审查有关言语(语音回路)和非言语(视觉空间暂存器)缓冲系统以及中枢执行功能缺陷的证据。在情节记忆的领域中,对证据的回忆和情节记忆的熟悉过程进行了审查。
更新日期:2019-11-01
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