West Nile virus (WNV) (Flavivirus: Flaviviridae) is the most widespread arbovirus in the world. A significant range expansion occurred beginning in 1999 when the virus was introduced into New York City. This review highlights recent research into WNV epizootiology and epidemiology, including recent advances in understanding of the host-virus interaction at the molecular, organismal, and ecological levels. Vector control strategies, vaccines, and antivirals, which now must be considered on a global scale, are also discussed.

中文翻译：

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西尼罗河病毒流行病学的全球视角。

西尼罗河病毒（WNV）（黄病毒：黄病毒科）是世界上分布最广泛的虫媒病毒。自1999年将病毒引入纽约市以来，病毒感染发生了很大的范围扩展。这篇综述重点介绍了对WNV流行病学和流行病学的最新研究，包括在分子，生物和生态水平上对宿主病毒相互作用的最新理解。还讨论了必须在全球范围内考虑的媒介控制策略，疫苗和抗病毒药。