Filamentous fungi are multicellular eukaryotic organisms known for nutrient recycling as well as for antibiotic and food production. This group of organisms also contains the most devastating plant pathogens and several important human pathogens. Since the first report of heterotrimeric G proteins in filamentous fungi in 1993, it has been demonstrated that G proteins are essential for growth, asexual and sexual development, and virulence in both animal and plant pathogenic filamentous species. Numerous G protein subunit and G protein-coupled receptor genes have been identified, many from whole-genome sequences. Several regulatory pathways have now been delineated, including those for nutrient sensing, pheromone response and mating, and pathogenesis. This review provides a comparative analysis of G protein pathways in several filamentous species, with discussion of both unifying themes and important unique signaling paradigms.

中文翻译：

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丝状真菌中的异三聚体G蛋白信号传导。

丝状真菌是多细胞真核生物，以营养物质循环以及抗生素和食品生产而著称。这组生物还包含最具破坏性的植物病原体和几种重要的人类病原体。自1993年首次报道丝状真菌中的异源三聚体G蛋白以来，已证明G蛋白对于动植物致病丝状物种的生长，无性和有性发育以及致病性至关重要。已经鉴定出许多G蛋白亚基和G蛋白偶联受体基因，其中许多来自全基因组序列。现在已经划定了几种调节途径，包括用于营养感测，信息素反应和交配以及发病机理的那些。这篇综述提供了几种丝状物种中G蛋白途径的比较分析，