Artificial selection has created myriad breeds of domestic animals, each characterized by unique phenotypes pertaining to behavior, morphology, physiology, and disease. Most domestic animal populations share features with isolated founder populations, making them well suited for positional cloning. Genome sequences are now available for most domestic species, and with them a panoply of tools including high-density single-nucleotide polymorphism panels. As a result, domestic animal populations are becoming invaluable resources for studying the molecular architecture of complex traits and of adaptation. Here we review recent progress and issues in the positional identification of genes underlying complex traits in domestic animals. As many phenotypes studied in animals are quantitative, we focus on mapping, fine mapping, and cloning of quantitative trait loci.

中文翻译：

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家畜定量性状基因座的作图，精细作图和分子解剖。

人工选择创造了无数种家畜，每一种都具有与行为，形态，生理和疾病有关的独特表型。大多数家畜种群与孤立的创始人种群具有共同的特征，使其非常适合于位置克隆。现在，大多数家庭物种都可以使用基因组序列，并且有了它们，包括高密度单核苷酸多态性面板在内的一整套工具。结果，家畜种群成为研究复杂性状和适应性分子结构的宝贵资源。在这里，我们回顾了家畜中复杂性状的基础基因定位的最新进展和问题。由于在动物中研究的许多表型都是定量的，因此我们专注于作图，精细作图，