I have dedicated the past 46 years of my life to science and I expect to be active in research for many more years. I have been lucky in my professional life. During my postdoctoral years I discovered two proteins that I showed to be involved in the initiation of protein synthesis. Working with bacteriophage ø29 for the past 40 years, we have made many interesting findings. Among them is the discovery of a protein covalently linked to the 5' ends of ø29 DNA that we later showed to be the primer for the initiation of ø29 DNA replication. Also, the finding of the ø29 DNA polymerase with its properties of high processivity, strand displacement, and high fidelity has been very rewarding. The ø29 DNA polymerase has become the ideal enzyme for DNA amplification, both rolling circle and whole-genome amplification. I also am happy because I have worked with many brilliant students and collaborators over the years, most of whom have become excellent scientists.

中文翻译：

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噬菌体ø29可使用40年。

我将生命的过去46年奉献给了科学，并且我希望自己能够继续从事研究工作很多年。我的职业生涯很幸运。在博士后的几年中，我发现了两种蛋白质，它们与蛋白质合成的启动有关。在过去的40年中，我们使用ø29噬菌体研究了许多有趣的发现。其中发现了与ø29DNA 5'端共价连接的蛋白质，我们后来证明它是引发ø29DNA复制的引物。同样，发现具有高加工性，链置换和高保真性的ø29DNA聚合酶也非常有意义。ø29DNA聚合酶已成为用于DNA扩增（滚环扩增和全基因组扩增）的理想酶。