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Plant ATP-Binding Cassette Transporters
Annual Review of Plant Biology ( IF 21.3 ) Pub Date : 2007-06-01 , DOI: 10.1146/annurev.arplant.57.032905.105406
Philip A Rea 1
Affiliation  

The ATP-binding cassette (ABC) protein superfamily is one of the largest known, with over 120 members in both Arabidopsis thaliana and rice (Oryza sativa). Most, but not all, ABC proteins are modularly organized membrane proteins ("ABC transporters") that mediate MgATP-energized transmembrane transport and/or regulate other transporters. The range of processes in which members of the various subclasses of plant ABC transporters have been implicated encompasses polar auxin transport, lipid catabolism, xenobiotic detoxification, disease resistance, and stomatal function. Although it is often possible to predict the likely function of a plant ABC transporter on the basis of its subfamily membership, there are many whose capabilities deviate from what would be predicted from the properties of even their most sequence-related counterparts. When taking account of this and the disparate processes in which the few that have been characterized participate, it is likely that elucidation of the mechanistic basis of any given plant process will necessitate consideration of at least one ABC transporter.

中文翻译:

植物 ATP 结合盒式转运蛋白

ATP 结合盒 (ABC) 蛋白超家族是已知最大的蛋白超家族之一,在拟南芥和水稻 (Oryza sativa) 中都有 120 多个成员。大多数(但不是全部)ABC 蛋白是模块化组织的膜蛋白(“ABC 转运蛋白”),可介导 MgATP 激活的跨膜转运和/或调节其他转运蛋白。涉及植物 ABC 转运蛋白各种亚类成员的过程范围包括极性生长素转运、脂质分解代谢、异生物质解毒、抗病性和气孔功能。虽然通常可以根据其亚科成员来预测植物 ABC 转运蛋白的可能功能,但仍有许多其能力与根据序列相关性最强的对应物的特性所预测的不同。
更新日期:2007-06-01
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