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Acute ischemic stroke: overview of recent therapeutic developments.
Annual Review of Medicine ( IF 10.5 ) Pub Date : 2007-01-16 , DOI: 10.1146/annurev.med.58.070605.115306
Nijasri Suwanwela 1 , Walter J Koroshetz
Affiliation  

Stroke, a disorder encompassing all cerebrovascular accidents, is a public health problem of immense proportions across the globe. Therapeutic efforts are directed at three aspects: prevention, acute treatment, and rehabilitation. Preventative measures, which in many instances mirror those for cardiovascular disease, can achieve the greatest public health impact. Measures that enhance the recovery of neurologic function and reduce neurologic disability after stroke can also affect a large population of handicapped stroke survivors. In the past 10 years, the greatest changes have occurred in the field of acute stroke treatment. Ultra-early-stage therapies with the potential to dramatically reverse severe neurologic deficits, or halt their progression, have caused a restructuring of the emergency care of neurologic patients. The parallels with the evolution of emergency treatment of acute coronary syndromes after 1970 are striking. This review focuses on aspects of stroke therapy that are either just entering, or soon to enter, current practice.

中文翻译:

急性缺血性中风:近期治疗进展的概述。

中风是一种涵盖所有脑血管意外的疾病,是全球范围内比例巨大的公共卫生问题。治疗工作着眼于三个方面:预防,急性治疗和康复。预防措施在许多情况下都反映出心血管疾病的预防措施,可以取得最大的公共卫生影响。增强中风后神经功能恢复和减少神经功能障碍的措施也可能影响大量的中风残障幸存者。在过去的十年中,急性中风治疗领域发生了最大的变化。超早期疗法具有显着逆转严重神经功能缺损或阻止其发展的潜力,已导致神经病患者的急诊护理结构调整。1970年后与急性冠状动脉综合症紧急治疗演变的相似之处引人注目。这篇综述着重于卒中治疗的各个方面,这些方面要么刚刚进入,要么即将进入当前实践。
更新日期:2019-11-01
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