Behavioral neurologists have long been interested in changes in religiosity following circumscribed brain lesions. Advances in neuroimaging and cognitive experimental techniques have been added to these classical lesion-correlational approaches in attempt to understand changes in religiosity due to brain damage. In this paper we assess processing dynamics of religious cognition in patients with Parkinson’s disease (PD). We administered a four-condition story-based priming procedure, and then covertly probed for changes in religious belief. Story-based priming emphasized mortality salience, religious ritual, and beauty in nature (Aesthetic). In neurologically intact controls, religious belief-scores significantly increased following the Aesthetic prime condition. When comparing effects of right (RO) versus left onset (LO) in PD patients, a double-dissociation in religious belief-scores emerged based on prime condition. RO patients exhibited a significant increase in belief following the Aesthetic prime condition and LO patients significantly increased belief in the religious ritual prime condition. Results covaried with executive function measures. This suggests lateral cerebral specialization for ritual-based (left frontal) versus aesthetic-based (right frontal) religious cognition. Patient-centered individualized treatment plans should take religiosity into consideration as a complex disease-associated phenomenon connected to other clinical variables and health outcomes.

中文翻译：

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帕金森病发病的侧面和宗教信仰的改变：新的行为表型。

长期以来，行为神经学家一直对局限性脑损伤后宗教信仰的变化感兴趣。神经影像学和认知实验技术的进步已被添加到这些经典的病变相关方法中，以试图了解由于脑损伤引起的宗教信仰的变化。在本文中，我们评估了帕金森病 (PD) 患者宗教认知的处理动态。我们执行了一个基于故事的四条件启动程序，然后秘密地探索宗教信仰的变化。基于故事的启动强调死亡的显着性、宗教仪式和自然之美（美学）。在神经功能完好的对照中，宗教信仰分数在美学初始条件下显着增加。当比较右侧 (RO) 与左侧 (LO) 对 PD 患者的影响时，基于素数条件的宗教信仰分数出现了双重分裂。RO 患者在美学初始条件下表现出信仰的显着增加，而 LO 患者对宗教仪式初始条件的信仰显着增加。结果与执行功能测量共变。这表明基于仪式的（左额叶）与基于审美的（右额叶）宗教认知的侧脑专业化。以患者为中心的个性化治疗计划应将宗教信仰作为一种与其他临床变量和健康结果相关的复杂疾病相关现象来考虑。RO 患者在美学初始条件下表现出信仰的显着增加，而 LO 患者对宗教仪式初始条件的信仰显着增加。结果与执行功能测量共变。这表明基于仪式的（左额叶）与基于审美的（右额叶）宗教认知的侧脑专业化。以患者为中心的个性化治疗计划应将宗教信仰作为一种与其他临床变量和健康结果相关的复杂疾病相关现象来考虑。RO 患者在美学初始条件下表现出信仰的显着增加，而 LO 患者对宗教仪式初始条件的信仰显着增加。结果与执行功能测量共变。这表明基于仪式的（左额叶）与基于审美的（右额叶）宗教认知的侧脑专业化。以患者为中心的个性化治疗计划应将宗教信仰作为一种与其他临床变量和健康结果相关的复杂疾病相关现象来考虑。