Novel ruthenium(III) complexes with histamine [RuCl(4)(dmso-S)(histamineH)] . H( (2) )O (1a) and [RuCl(4)(dmso-S)(histamineH)] (1b) have been prepared and characterized by X-ray structure analysis. Their crystal structures are similar and show a protonated amino group on the side chain of the ligand which is not very common for a simple heterocyclic derivative such as histamine. Biological assays to test the cytotoxicity of the compound 1b combined with electroporation were performed to determine its potential for future medical applications in cancer treatment.

中文翻译：

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新型钌 (III) 与组胺配合物的合成和表征。

新型钌 (III) 与组胺 [RuCl(4)(dmso-S)(histamineH)] 络合物。H( (2) )O (1a) 和 [RuCl(4)(dmso-S)(histamineH)] (1b) 已制备并通过 X 射线结构分析表征。它们的晶体结构相似，并在配体的侧链上显示出质子化的氨基，这对于简单的杂环衍生物（如组胺）来说并不常见。进行了测试化合物 1b 与电穿孔相结合的细胞毒性的生物测定，以确定其在未来癌症治疗中的医学应用的潜力。