Fructose is one of the most abundant monosaccharide in nature. It is also the sweetest naturally occurring carbohydrate. Since decades, fructose used for food preparations is not provided by fruit or vegetable but by a chemical process of starch or inulin conversion. We processed a new method of fructose extraction from apple and investigated the acute and long term effect of this carbohydrate on glucose metabolism in C57Bl6/j mice. By using the glycemic index (GI), we have shown that one of the sugars obtained from apple, FructiLight, has a very low impact on glycemic and insulin response during acute treatment compared to other sugars. This carbohydrate, essentially constituted by fructose, has also beneficial properties when administrated for long term treatment. Indeed, as two other sugars extracted from apple (FructiSweetApple and FructiSweet67), FructiLight exposure during 21 weeks in beverage has promoted an enhancement of glucose tolerance compared to glucose treatment without affecting food intake and weight. All these results indicate that apple-extracted sugars and more precisely fructose from these fruits could be a promising way to produce new food and sweet beverages.

中文翻译：

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从苹果中提取的天然果糖可改善小鼠的葡萄糖耐量。

果糖是自然界中含量最丰富的单糖之一。它也是最甜的天然碳水化合物。几十年来，用于食品制备的果糖不是由水果或蔬菜提供，而是由淀粉或菊粉转化的化学过程提供。我们处理了一种从苹果中提取果糖的新方法，并研究了这种碳水化合物对 C57Bl6/j 小鼠葡萄糖代谢的急性和长期影响。通过使用血糖指数 (GI)，我们表明，与其他糖类相比，从苹果中提取的一种糖类 FructiLight 在急性治疗期间对血糖和胰岛素反应的影响非常低。这种主要由果糖构成的碳水化合物在长期治疗时也具有有益的特性。的确，作为从苹果中提取的另外两种糖（FructiSweetApple 和 FructiSweet67），与葡萄糖治疗相比，在饮料中 21 周的 FructiLight 暴露促进了葡萄糖耐量的增强，而不影响食物摄入量和体重。所有这些结果表明，从这些水果中提取苹果糖，更准确地说是果糖，可能是生产新食品和甜饮料的一种很有前途的方法。