Sphingolipidomics, a branch of lipidomics, focuses on the large-scale study of the cellular sphingolipidomes. In the current review, two main approaches for the analysis of cellular sphingolipidomes (i.e. LC-MS- or LC-MS/MS-based approach and shotgun lipidomics-based approach) are briefly discussed. Their advantages, some considerations of these methods, and recent applications of these approaches are summarized. It is the authors' sincere hope that this review article will add to the readers understanding of the advantages and limitations of each developed method for the analysis of a cellular sphingolipidome.

中文翻译：

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适用于鞘脂组学的脂质组学技术及其相关应用综述

鞘脂组学是脂质组学的一个分支，专注于细胞鞘脂组的大规模研究。在当前的审查中，简要讨论了细胞鞘脂组分析的两种主要方法（即基于 LC-MS 或 LC-MS/MS 的方法和基于鸟枪脂质组学的方法）。总结了它们的优点、这些方法的一些考虑因素以及这些方法的最新应用。作者真诚地希望这篇评论文章能让读者了解每种已开发的细胞鞘脂组分析方法的优点和局限性。