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Effect of ABCG2, PPARGC1A, OLR1 and SCD1 gene polymorphism on estimated breeding values for functional and production traits in Polish Holstein-Friesian bulls.
Journal of Applied Genetics ( IF 2.0 ) Pub Date : 2009 , DOI: 10.1007/bf03195663
J Komisarek 1 , Z Dorynek
Affiliation  

This study investigated the impact of 6 polymorphisms located in theABCG2, PPARGC1A, OLR1 andSCD1 genes on estimated breeding values for milk production, longevity, somatic cell count and reproductive traits. The analysis was conducted on 453 Polish Holstein-Friesian bulls. Genotypes were identified using PCR-RFLP, and haplotype inferences were performed for 3 linked mutations ofPPARGC1A. The most significant associations were found between the A/C polymorphism located in exon 14 ofABCG2 and milk fat production traits as well as calving-to-first insemination interval, and between the T/C substitution in intron 9 of thePPARGC1A and non-return rate in heifers.

中文翻译:

ABCG2、PPARGC1A、OLR1 和 SCD1 基因多态性对波兰荷斯坦弗里斯兰公牛功能和生产性状估计育种值的影响。

本研究调查了位于ABCG2、PPARGC1A、OLR1SCD1基因中的 6 个多态性对产奶量、寿命、体细胞计数和生殖性状的估计育种值的影响。分析是对 453 头波兰荷斯坦-弗里斯兰公牛进行的。使用 PCR-RFLP 鉴定基因型,并对PPARGC1A 的3 个连锁突变进行单倍型推断。发现位于ABCG2外显子 14 的 A/C 多态性与乳脂生产性状以及产犊至第一次授精间隔之间以及PPARGC1A内含子 9 中的 T/C 替换与非小母牛的回报率。
更新日期:2020-09-22
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