Seizures do not occur randomly in the majority of people with epilepsy. They tend to cluster. Seizure clusters, in turn, commonly occur with a temporal rhythmicity that shows a readily identifiable and predictable periodicity. When the periodicity of seizure exacerbation in women conforms to that of the menstrual cycle, it is commonly known as catamenial epilepsy. This may be attributable to 1) the neuroactive properties of steroid hormones and 2) the cyclic variation in their serum levels. If hormones play a role in seizure occurrence, hormones may also have a role in treatment. Progesterone has potent GABAergic metabolites that may provide safe and effective seizure control in women who have catamenial epilepsy.

中文翻译：

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激素疗法：黄体酮。


大多数癫痫患者的癫痫发作并不是随机发生的。他们倾向于聚集。反过来，癫痫发作通常具有时间节奏，显示出易于识别和预测的周期性。当女性癫痫发作的周期性与月经周期一致时，通常称为月经期癫痫。这可能归因于 1) 类固醇激素的神经活性特性和 2) 其血清水平的周期性变化。如果激素在癫痫发作中发挥作用，那么激素也可能在治疗中发挥作用。黄体酮具有有效的 GABA 能代谢物，可以为患有经期癫痫的女性提供安全有效的癫痫发作控制。