There are many theories of aging and a number ofthem encompass the role of mitochondria in this process. Mitochondrial DNA mutations and deletions have been shown to accumulate in many tissues in mammals during aging. However, there is little evidence that these mutations could affect the functioning of aging tissues.

中文翻译：

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线粒体和衰老：无辜的旁观者还是有罪的一方？

有许多关于衰老的理论，其中一些包含线粒体在这个过程中的作用。线粒体 DNA 突变和缺失已被证明在衰老过程中会在哺乳动物的许多组织中积累。然而，几乎没有证据表明这些突变会影响衰老组织的功能。