An experiment investigated the effect of different selenium supplementations on the antioxidant defence system and on the occurrence of muscle dystrophy in growing turkeys. Newly hatched male turkeys (B.U.T. Big 6) were divided into eight groups of 18 turkeys each and fed either a basal diet (selenium <0.010 mg/kg diet), or the basal diet supplemented with 0.10; 0.15; 0.20; 0.25; 0.30; 0.35 or 0.40 mg selenium/kg diet in the form of sodium selenate. Vitamin E was adequately supplemented in all diets. After 35 days, muscle damage parameters including aspartate aminotransferase, creatine kinase, creatine kinase M and B were significantly increased in the selenium deficient Group I. A significant reduction of weight gain, feed consumption and selenium dependent glutathione peroxidase activity was also observed in the liver of selenium deficient birds. The ratio of oxidised glutathione (GSSG) to total glutathione (tGSH) was substantially altered in the selenium deficient Group I as well as in Group II (0.10 mg selenium/kg feed). The activity of glutathione reductase (GR) and glutathione-S-transferase (GST) was not affected by selenium deficiency.

中文翻译：

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硒缺乏对生长火鸡抗氧化状态和肌肉损伤的影响

一项实验研究了不同硒补充剂对抗氧化防御系统和生长火鸡肌肉营养不良发生的影响。新孵化的雄性火鸡（BUT Big 6）被分成八组，每组 18 只火鸡，饲喂基础日粮（硒 <0.010 mg/kg 日粮）或补充 0.10 硒的基础日粮；0.15; 0.20; 0.25; 0.30; 硒酸钠形式的 0.35 或 0.40 毫克硒/公斤饮食。在所有饮食中都充分补充了维生素 E。35 天后，缺硒组 I 的肌肉损伤参数，包括天冬氨酸转氨酶、肌酸激酶、肌酸激酶 M 和 B 显着增加。体重增加显着减少，在缺硒鸟类的肝脏中也观察到饲料消耗和硒依赖性谷胱甘肽过氧化物酶活性。氧化型谷胱甘肽 (GSSG) 与总谷胱甘肽 (tGSH) 的比率在缺硒组 I 和组 II（0.10 毫克硒/千克饲料）中发生了显着变化。谷胱甘肽还原酶 (GR) 和谷胱甘肽-S-转移酶 (GST) 的活性不受硒缺乏的影响。