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Transport of carboxylic acids in yeasts.
FEMS Microbiology Reviews ( IF 11.3 ) Pub Date : 2008-09-02 , DOI: 10.1111/j.1574-6976.2008.00128.x
Margarida Casal 1 , Sandra Paiva , Odília Queirós , Isabel Soares-Silva
Affiliation  

Carboxylic acid transporters form a heterogeneous group of proteins, presenting diverse mechanisms of action and regulation, and belonging to several different families. Multiple physiological and genetic studies in several organisms, from yeast to mammals, have allowed the identification of various genes coding for carboxylate transporters. Detailed understanding of the metabolism and transport of these nutrients has become more important than ever, both from a fundamental and from an applied point of view. Under a biotechnological perspective, the increasing economic value of these compounds has boosted this field of research considerably. Here we review the current knowledge on yeast carboxylate transporters, at the biochemical and molecular level, focusing also on recent biotechnological developments.

中文翻译:

酵母中羧酸的运输。

羧酸转运蛋白形成蛋白质的异质性组,呈现出不同的作用和调节机制,并且属于几个不同的家族。从酵母到哺乳动物,在多种生物中进行了多种生理和遗传研究,从而鉴定出各种编码羧酸盐转运蛋白的基因。从基础和应用的角度来看,对这些营养素的代谢和运输的详细了解比以往任何时候都变得更加重要。从生物技术的角度看,这些化合物的日益增长的经济价值大大促进了这一研究领域。在这里,我们回顾了在生物化学和分子水平上关于酵母羧酸盐转运蛋白的最新知识,同时也关注了最新的生物技术发展。
更新日期:2019-11-01
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