A series of adenylyl-(5' yields N)-omega-arylalkylamines, containing from one to six methylene groups in the amino component, was studied by methods of nuclear magnetic resonance and circular dichroism. It was shown that independently of the length of the aliphatic chain of the amine convergence of the adenine and benzene rings and a hydrophobic interaction between them occur. The plane of the benzene ring is inclined toward the adenine ring, which has an anticonformation relative to the ribose. The structure of the intramolecular complex and the energy of the interaction of the aromatic systems of the amine and nucleotide depend on the number of methylene groups in the amino component. Maximum interaction occurs in the presence of two methylene groups; weakening of the interaction occurs with an increase in the chain to four links, which does not change upon further lengthening of the chain. The conformation of adenylyl-(5' yields N)-benzylamine differs from the structure of the other compounds of the series investigated.

中文翻译：

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苯环和腺嘌呤环的非共价相互作用取决于它们在腺苷基-（5'中的距离）之间的距离，得到N）-ω-芳基烷基胺。

通过核磁共振和圆二色性的方法研究了一系列在氨基组分中含有1至6个亚甲基的腺苷基-（5'生成N）-ω-芳基烷基胺。已表明，与胺的脂族链的长度无关，腺嘌呤和苯环的会聚以及它们之间发生疏水相互作用。苯环的平面朝向腺嘌呤环倾斜，该腺嘌呤环相对于核糖具有反构象。分子内复合物的结构以及胺和核苷酸的芳族系统相互作用的能量取决于氨基组分中亚甲基的数目。在两个亚甲基的存在下发生最大的相互作用。随着链条增加到四个链接，交互作用会减弱，随着链条的进一步延长，它不会改变。腺苷基-（5'产生N）-苄胺的构象与所研究系列的其他化合物的结构不同。