For the diagnosis of atherosclerosis, biomedical imaging techniques such as intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have been developed. The combined use of IVUS and OCT is hypothesized to remarkably increase diagnostic accuracy of vulnerable plaques. We have developed an integrated IVUS-OCT imaging apparatus, which includes the integrated catheter, motor drive unit, and imaging system. The dual-function imaging catheter has the same diameter of current clinical standard. The imaging system is capable for simultaneous IVUS and OCT imaging in real time. Ex vivo and in vivo experiments on rabbits with atherosclerosis were conducted to demonstrate the feasibility and superiority of the integrated intravascular imaging modality.

中文翻译：

---

用于动脉粥样硬化斑块表征的集成 IVUS-OCT 成像

对于动脉粥样硬化的诊断，已经开发了生物医学成像技术，例如血管内超声 (IVUS) 和光学相干断层扫描 (OCT)。假设 IVUS 和 OCT 的联合使用可显着提高易损斑块的诊断准确性。我们开发了集成 IVUS-OCT 成像设备，其中包括集成导管、电机驱动单元和成像系统。双功能成像导管的直径与当前临床标准相同。该成像系统能够实时同时进行 IVUS 和 OCT 成像。对患有动脉粥样硬化的兔子进行了体外和体内实验，以证明集成血管内成像模式的可行性和优越性。