Meal replacements and viscous soluble fibre represent safe and sustainable aids for weight loss. Our purpose was to determine if PGX® meal replacements and PGX^® fibre complex in combination with a calorie-restricted diet would aid in weight loss in a clinical setting. Fifty-two overweight and obese participants (49 women, 3 men; average age 47.1 years) with a mean body mass index (BMI) of 33.8 ± 6.4 kg/m² consumed 57 g of proprietary PGX® meal replacement product at breakfast and another 57 g at lunch for 12 weeks. In addition to the meal replacements, they were also asked to consume 5 g/day of PGX® fibre in the form of granules, powder or capsules together with 250 mlwater. A registered dietician recommended low-fat, low-glycaemic-index foods for snacks and the dinner menus such that each volunteer was consuming a total of 1200 kcal/day. All participants (n = 52) lost a significant amount of weight from baseline (−4.69 ± 3.73 kg), which was further reflected in the reductions in their waist (−7.11 ± 6.35 cm) and hip circumference (−5.59 ± 3.58 cm) over the 12-week study (p < 0.0001). BMI scores (n = 51) were reduced by 1.6 ± 1.4 kg/m². The use of PGX® meal replacements and PGX^® fibre along with a controlled dietary caloric intake is of benefit for short-term weight loss.

代餐和粘性可溶性纤维代表了减肥的安全和可持续的辅助手段。我们的目的是确定是否PGX®代餐和PGX ^®纤维结合复杂与限制热量饮食会帮助减肥在临床环境中。52名超重和肥胖参与者（49名女性，3名男性；平均年龄47.1岁），平均体重指数（BMI）为33.8±6.4 kg / m ²早餐时食用了57克专有的PGX®代餐产品，午餐时又食用了57克，持续12周。除了代餐外，他们还被要求每天以颗粒，粉末或胶囊的形式消耗5 g /天的PGX®纤维以及250毫升水。注册的营养师推荐使用低脂，低血糖指数的食品作为小吃和晚餐菜单，这样每位志愿者每天的总消耗量为1200 kcal。所有参与者（n = 52）比基线（−4.69±3.73 kg）减轻了很多重量，这进一步体现在腰部（−7.11±6.35 cm）和臀围（−5.59±3.58 cm）的减少上在为期12周的研究中（p <0.0001）。BMI分数（n = 51）降低了1.6±1.4 kg / m ²。使用PGX®代餐和PGX的^® 纤维和控制饮食热量的摄入有益于短期减肥。