Children raised in poverty are prone to physical health problems late in life. To understand these findings and address the scientific challenge they represent, we must formulate integrative conceptual frameworks at the crossroads of behavioral and biomedical science, with a strong developmental emphasis. In this article, we outline such a framework and discuss research bearing on its validity. We address how childhood poverty gets under the skin, at the level of tissues and organs, in a manner that affects later disease risks. We also tackle questions about resilience; even with lengthy exposure to childhood poverty, why does only a subset of people acquire diseases? Why are some individuals protected whereas others remain vulnerable? Maternal nurturance might be a source of resilience, buffering children from the long‐term health consequences of poverty. We conclude with research priorities.

中文翻译：

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儿童贫困的生物残留。

在贫困中长大的儿童在晚年容易出现身体健康问题。为了理解这些发现并解决它们所代表的科学挑战，我们必须在行为和生物医学科学的十字路口制定综合概念框架，并强调发展重点。在本文中，我们概述了这样一个框架并讨论了对其有效性的研究。我们解决了儿童贫困如何在组织和器官层面以影响后期疾病风险的方式深入人心。我们还解决了有关弹性的问题；即使长期处于儿童贫困之中，为什么只有一部分人会患上疾病？为什么有些人受到保护，而另一些人仍然脆弱？母亲的养育可能是恢复力的来源，使儿童免受贫困的长期健康影响。我们以研究重点结束。