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Inherited Representations are Read in Development
The British Journal for the Philosophy of Science ( IF 3.2 ) Pub Date : 2013-03-01 , DOI: 10.1093/bjps/axr050
Nicholas Shea 1
Affiliation  

Recent theoretical work has identified a tightly constrained sense in which genes carry representational content. Representational properties of the genome are founded in the transmission of DNA over phylogenetic time and its role in natural selection. However, genetic representation is not just relevant to questions of selection and evolution. This article goes beyond existing treatments and argues for the heterodox view that information generated by a process of selection over phylogenetic time can be read in ontogenetic time, in the course of individual development. Recent results in evolutionary biology, drawn both from modelling work, and from experimental and observational data, support a role for genetic representation in explaining individual ontogeny: both genetic representations and environmental information are read by the mechanisms of development, in an individual, so as to lead to adaptive phenotypes. Furthermore, in some cases there appears to have been selection between individuals that rely to different degrees on the two sources of information. Thus, the theory of representation in inheritance systems like the genome is much more than just a coherent reconstruction of information talk in biology. Genetic representation is a property with considerable explanatory utility. 1 Introduction 2 Inherited Representations 3 Reading Genetic Representations 3.1 Do genes carry correlational information? 4 Selection Between Genetic and Environmental Information 4.1 Modelling 4.2 Empirical applications 4.3 Maternal effects 5 Genetic Representation and the Genome 5.1 Information capacity of organisms' genomes 5.2 Many amino acids, few nucleotides 5.3 A function of sex 6 Explaining Further Aspects of Development 6.1 Canalization against environmental variation 6.2 An informational function for the nuclear membrane? 7 Conclusion 1 Introduction 2 Inherited Representations 3 Reading Genetic Representations 3.1 Do genes carry correlational information? 3.1 Do genes carry correlational information? 4 Selection Between Genetic and Environmental Information 4.1 Modelling 4.2 Empirical applications 4.3 Maternal effects 4.1 Modelling 4.2 Empirical applications 4.3 Maternal effects 5 Genetic Representation and the Genome 5.1 Information capacity of organisms' genomes 5.2 Many amino acids, few nucleotides 5.3 A function of sex 5.1 Information capacity of organisms' genomes 5.2 Many amino acids, few nucleotides 5.3 A function of sex 6 Explaining Further Aspects of Development 6.1 Canalization against environmental variation 6.2 An informational function for the nuclear membrane? 6.1 Canalization against environmental variation 6.2 An informational function for the nuclear membrane? 7 Conclusion

中文翻译:

继承的表示在开发中被读取

最近的理论工作已经确定了基因携带代表性内容的严格限制意义。基因组的代表性特性建立在 DNA 在系统发育时间的传递及其在自然选择中的作用中。然而,遗传表征不仅仅与选择和进化问题相关。本文超越了现有的治疗方法,并主张非正统观点,即系统发育时间选择过程产生的信息可以在个体发育过程中的个体发育时间中被读取。进化生物学的最新结果来自建模工作以及实验和观察数据,支持遗传表征在解释个体个体发育中的作用:遗传表征和环境信息都是由个体的发育机制读取的,因此导致适应性表型。此外,在某些情况下,似乎在不同程度上依赖这两种信息来源的个人之间进行了选择。因此,基因组等遗传系统的表征理论不仅仅是生物学中信息对话的连贯重建。遗传表征是一种具有相当大的解释效用的属性。1 简介 2 遗传表征 3 解读遗传表征 3.1 基因是否携带相关信息?4 遗传信息和环境信息之间的选择 4.1 建模 4.2 实证应用 4.3 母体效应 5 遗传表征和基因组 5.1 生物体基因组的信息能力 5.2 氨基酸较多,核苷酸较少 5.3 性别功能 6 解释发展的其他方面 6.1 运河化对环境的影响变异 6.2 核膜的信息功能?7 结论 1 简介 2 遗传表征 3 解读遗传表征 3.1 基因是否携带相关信息?3.1 基因是否携带相关信息?4 遗传信息和环境信息之间的选择 4.1 建模 4.2 实证应用 4.3 母体效应 4.1 建模 4.2 实证应用 4.3 母体效应 5 遗传表征和基因组 5.1 生物体基因组的信息能力 5.2 多种氨基酸,少量核苷酸 5.3 性别函数 5.1 信息生物体基因组的能力 5.2 氨基酸较多,核苷酸较少 5.3 性别功能 6 解释发育的其他方面 6.1 对抗环境变化的渠道化 6.2 核膜的信息功能?6.1 针对环境变化的渠道化 6.2 核膜的信息功能?7 结论
更新日期:2013-03-01
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