Various procedures involving stimulations of facial regions are known to induce so-called trigemino-cardiac reflexes that entail a decrease of heart rate and blood pressure. We here report the effects of a specific stimulation that consists in a submaximal passive mandibular extension obtained by means of a dilatator applied for 10 minutes between the upper and lower incisor teeth, associated with partial active masticatory movements. Blood pressure and heart rate were determined in 18 young normal volunteers by Omron M4, before (20 minutes), during (10 minutes) and after mandibular extension (80 minutes) and under control conditions (same overall duration without stimulation). While control values remained stable, mandibular extension was followed by a progressive decline of both blood pressure (up to about 12/11 mmHg) and heart rate (up to about 13 bpm), statistically confirmed by ANOVA both on absolute values and on changes from basal values. The decline of systolic blood pressure and heart rate significantly correlated with basal values. The present findings indicate that submaximal opening of the mouth, associated to partial masticatory movements, induces a prolonged reduction of blood pressure and heart rate in normotensive volunteers.

中文翻译：

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被动下颌伸展的长期降压和心动过缓作用：正常志愿者的证据。

已知涉及刺激面部区域的各种程序会引起所谓的三叉神经-心脏反射，其导致心率和血压降低。我们在这里报告了一种特定刺激的效果，该刺激包括通过在上，下切牙之间施加10分钟的扩张器而获得的最大程度的被动下颌延伸，并伴有部分主动咀嚼运动。在18个年轻的正常志愿者中，在欧姆龙M4之前（20分钟），下颌（10分钟）和下颌延长后（80分钟）以及在对照条件下（相同的总持续时间，无刺激）测定血压和心率。虽然控制值保持稳定，下颌伸展后，血压（最高约12/11 mmHg）和心率（最高约13 bpm）均逐渐下降，ANOVA绝对值和基础值的变化均通过统计学证实。收缩压和心率的下降与基础值显着相关。目前的发现表明，与正常咀嚼运动有关的最大张口是在血压正常的志愿者中导致血压和心率的长期降低。