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Effect of modifying quantum dot surface charge on airway epithelial cell uptake in vitro.
Nanotoxicology ( IF 5 ) Pub Date : 2012-08-20 , DOI: 10.3109/17435390.2012.711862
Eric Chau 1 , Justin F Galloway , Antoinette Nelson , Patrick N Breysse , Denis Wirtz , Peter C Searson , Venkataramana K Sidhaye
Affiliation  

The respiratory system is one of the portals of entry into the body, and hence inhalation of engineered nanomaterials is an important route of exposure. The broad range of physicochemical properties that influence biological responses necessitate the systematic study to contribute to understanding occupational exposure. Here, we report on the influence of nanoparticle charge and dose on human airway epithelial cells, and show that this platform can be used to evaluate consequences of exposure to engineered nanomaterials.

中文翻译:

修饰量子点表面电荷对体外气道上皮细胞摄取的影响。

呼吸系统是进入人体的门户之一,因此吸入工程纳米材料是重要的暴露途径。影响生物反应的广泛物理化学特性需要系统研究,以有助于了解职业暴露。在这里,我们报告了纳米粒子电荷和剂量对人类气道上皮细胞的影响,并表明该平台可用于评估暴露于工程纳米材料的后果。
更新日期:2019-11-01
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