Environmental conditions play an important role in conceptual studies of prebiotically relevant chemical reactions that could have led to functional biomolecules. The necessary source compounds are likely to have been present in dilute solution, raising the question of how to achieve selective concentration and to reach activation. With the assumption of an initial 'RNA World', the questions of production, concentration, and interaction of aldehydes and aldehyde phosphates, potential precursors of sugar phosphates, come into the foreground. As a possible concentration process for simple, uncharged aldehydes, we investigated their adduct formation with sulfite ion bound in the interlayer of positively charged expanding-sheet-structure double-layer hydroxide minerals. Minerals of this type, initially with chloride as interlayer counter anion, have previously been shown to induce concentration and subsequent aldolization of aldehyde phosphates to form tetrose, pentose, and hexose phosphates. The reversible uptake of the simple aldehydes formaldehyde, glycolaldehyde, and glyceraldehyde by adduct formation with the immobilized sulfite ions is characterized by equilibrium constants of K=1.5, 9, and 11, respectively. This translates into an observable uptake at concentrations exceeding 50 mM.

中文翻译：

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含亚硫酸​​盐的双层氢氧化物矿物对简单醛的浓缩：对生物生成的影响。

环境条件在可能导致功能性生物分子发生的益生元相关化学反应的概念研究中起着重要作用。稀溶液中可能已经存在必需的来源化合物，这引发了如何实现选择性浓缩并达到活化的问题。在最初的“ RNA世界”的假设下，醛糖磷酸酯和醛磷酸酯（糖磷酸酯的潜在前体）的产生，浓度和相互作用的问题成为人们关注的焦点。作为简单的不带电荷的醛的一种可能的浓缩过程，我们研究了亚硫酸根离子结合在带正电的扩展板结构的双层氢氧化物矿物的中间层中加成物的形成。这种类型的矿物质，最初以氯离子作为层间抗衡阴离子，先前已显示出其可诱导磷酸醛醛的浓缩和随后的醛醇缩合，以形成四氢蔗糖，戊糖和己糖磷酸酯。通过与固定的亚硫酸根离子形成加合物可逆地吸收简单的醛，甲醛，乙醇醛和甘油醛的特点是平衡常数分别为K = 1.5、9和11。转化为浓度超过50 mM时可观察到的摄取。