Nanomaterials obtained by green synthesis technologies have been widely studied in recent years owing to constitute cost-effective and environmental-friendly methods. In addition, there are several works that report the simultaneous performance of the reducer agent as a functionalizing agent, modifying the properties of the nanomaterial. As a simple and economical synthesis methodology, this work presents a method to synthesize silver nanoparticles (AgNPs) using Annona muricata aqueous extract and functionalized with 5-fluorouracil (5-FU). The processes of reduction, nucleation, and functionalization of the nanoparticles were analyzed by UV-Vis absorption spectroscopy, and it was found that they are the function of the contact time of the metal ions with the extract. The structural characterization was carried out by transmission electron microscopy (TEM) and X-ray diffraction patterns (XRD). The antibacterial properties of the synthetized nanomaterials were tested using minimum inhibitory concentration (MIC) and minimum bactericidal concentration (MBC) against Enterococcus faecalis, Staphylococcus aureus, and Escherichia coli growth.

中文翻译：

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绿色合成方法获得的银纳米颗粒的细胞毒性和杀菌作用，该合成方法使用了栗色番荔枝水提取物并用5-氟尿嘧啶官能化。

由于绿色合成技术获得的纳米材料具有成本效益和环境友好的方法，因此近年来已被广泛研究。另外，有几篇工作报道了还原剂作为功能化剂的同时性能，改变了纳米材料的性能。作为一种简单而经济的合成方法，这项工作提出了一种使用Annona muricata合成银纳米颗粒（AgNPs）的方法。水提取物并用5-氟尿嘧啶（5-FU）官能化。通过UV-Vis吸收光谱法分析了纳米颗粒的还原，成核和功能化过程，发现它们是金属离子与提取物接触时间的函数。通过透射电子显微镜（TEM）和X射线衍射图（XRD）进行结构表征。使用对粪肠球菌，金黄色葡萄球菌和大肠杆菌生长的最小抑菌浓度（MIC）和最小杀菌浓度（MBC）测试了合成纳米材料的抗菌性能。