Auditory function takes a major part in human life. While sensorineural hearing loss is related with many factors including genetic disorders, age and noise, the clear causes are not well understood. Even more, the currently available treatments with drugs cause side effects, which thus are considered suboptimal. Here, we communicate the delivery systems with biomaterials that can be possible therapeutic options to restore hearing and vestibular functions. We introduce briefly the various pathological factors related with hearing loss and the limitation of current therapies, detail the recent studies on delivery systems including nanoparticles and hydrogels and discuss future clinical availability.

中文翻译：

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听觉障碍和未来治疗与输送系统。

听觉功能在人类生活中占有重要地位。虽然感觉神经性听力损失与许多因素有关，包括遗传疾病，年龄和噪音，但不清楚的原因尚不清楚。甚至更多，当前可用的药物治疗引起副作用，因此被认为是次优的。在这里，我们将传递系统与生物材料进行交流，这可能是恢复听力和前庭功能的治疗选择。我们简要介绍了与听力损失和当前疗法的局限性相关的各种病理因素，详细介绍了包括纳米颗粒和水凝胶在内的输送系统的最新研究，并讨论了未来的临床可行性。