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Dexmedetomidine Ameliorates Sleep Deprivation-Induced Depressive Behaviors in Mice.
International Neurourology Journal ( IF 1.8 ) Pub Date : 2018-10-31 , DOI: 10.5213/inj.1836228.114
Eun-Jin Moon 1 , Il-Gyu Ko 2 , Sung-Eun Kim 2 , Jun-Jang Jin 2 , Lakkyong Hwang 2 , Chang-Ju Kim 2 , Hyeonjun An 1 , Bong-Jae Lee 1 , Jae-Woo Yi 1
Affiliation  

Sleep deprivation induces depressive symptoms. Dexmedetomidine is a α2-adrenoreceptor agonist and this drug possesses sedative, anxiolytic, analgesic, and anesthetic-sparing effect. In this study, the action of dexmedetomidine on sleep deprivation-induced depressive behaviors was investigated using mice.

中文翻译:

右美托咪定改善小鼠睡眠剥夺诱导的抑郁行为。

睡眠不足会引起抑郁症状。右美托咪定是一种α2-肾上腺素受体激动剂,该药物具有镇静,抗焦虑,镇痛和麻醉剂的保护作用。在这项研究中,使用小鼠研究了右美托咪定对睡眠剥夺引起的抑郁行为的作用。
更新日期:2020-08-21
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