Postural orthostatic tachycardia syndrome (POTS) is a disabling condition characterized by orthostatic intolerance with tachycardia in the absence of drop-in blood pressure. A custom-built near-infrared spectroscopy device (NIRS) is applied to monitor the muscle oxygenation, noninvasively in patients undergoing incremental head-up tilt table (HUT). Subjects (6 POTS patients and 6 healthy controls) underwent 30[Formula: see text]mins of 70∘ on a HUT. The results showed a significant difference in deoxyhemoglobin (Hb), change-in-oxygenation [Formula: see text] and blood volume [Formula: see text] between patients and healthy controls. However, oxyhemoglobin (HbO2) showed a significantly faster rate of change in the healthy controls during the first 10[Formula: see text]mins of the tilt and during the recovery. This NIRS muscle oximetry tool provides quantitative measurements of blood oxygenation monitoring in diseases such as POTS.

中文翻译：

---

体位性心动过速综合征患者的近红外光谱肌血氧测定


体位性直立性心动过速综合征 (POTS) 是一种致残性疾病，其特征是在没有血压下降的情况下不能耐受直立性心动过速。定制的近红外光谱装置 (NIRS) 用于无创监测接受增量平视倾斜台 (HUT) 的患者的肌肉氧合情况。受试者（6 名 POTS 患者和 6 名健康对照）接受 70 次 30[公式：见文本]分钟∘在小屋里。结果显示，患者和健康对照者之间的脱氧血红蛋白 (Hb)、氧合变化 [公式：见正文] 和血容量 [公式：见正文] 存在显着差异。然而，氧合血红蛋白 (HbO 2 ）显示，在倾斜的前 10[公式：见文本]分钟和恢复过程中，健康对照组的变化率明显更快。这款 NIRS 肌肉血氧测定工具可对 POTS 等疾病的血氧监测进行定量测量。