Cell migration requires the coordinated activation of structural and signalling molecules, such as the RhoGTPase Rac1. It is known that the nicotinamide adenine dinucleotide phosphate (NADPH) oxidase complex assembly, which generates reactive oxygen species (ROS) at the cell membrane, also relies on Rac1 activation, indicating a possible effect of ROS during cell migration. In this study, we evaluated the effect of NADPH‐oxidase‐derived ROS on the migration process.

中文翻译：

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NADPH 氧化酶衍生的 ROS 通过调节粘附动力学改变细胞迁移

细胞迁移需要结构和信号分子的协同激活，例如 RhoGTPase Rac1。众所周知，在细胞膜上产生活性氧 (ROS) 的烟酰胺腺嘌呤二核苷酸磷酸 (NADPH) 氧化酶复合体组装也依赖于 Rac1 激活，表明 ROS 在细胞迁移过程中可能产生影响。在这项研究中，我们评估了 NADPH 氧化酶衍生的 ROS 对迁移过程的影响。