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PlaNC-TE: a comprehensive knowledgebase of non-coding RNAs and transposable elements in plants.
Database: The Journal of Biological Databases and Curation ( IF 5.8 ) Pub Date : 2018-09-13 , DOI: 10.1093/database/bay078
Daniel Longhi Fernandes Pedro 1 , Alan Péricles Rodrigues Lorenzetti 2 , Douglas Silva Domingues 1, 3 , Alexandre Rossi Paschoal 1
Affiliation  

Transposable elements (TEs) play an essential role in the genetic variability of eukaryotic species. In plants, they may comprise up to 90% of the total genome. Non-coding RNAs (ncRNAs) are known to control gene expression and regulation. Although the relationship between ncRNAs and TEs is known, obtaining the organized data for sequenced genomes is not straightforward. In this study, we describe the PlaNC-TE (http://planc-te.cp.utfpr.edu.br), a user-friendly portal harboring a knowledgebase created by integrating and analysing plant ncRNA-TE data. We identified a total of 14 350 overlaps between ncRNAs and TEs in 40 plant genomes. The database allows users to browse, search and download all ncRNA and TE data analysed. Overall, PlaNC-TE not only organizes data and provides insights about the relationship between ncRNA and TEs in plants but also helps improve genome annotation strategies. Moreover, this is the first database to provide resources to broadly investigate functions and mechanisms involving TEs and ncRNAs in plants.

中文翻译:

PlaNC-TE:植物中非编码RNA和转座因子的综合知识库。

转座因子(TEs)在真核生物的遗传变异中起着至关重要的作用。在植物中,它们可能占总基因组的90%。已知非编码RNA(ncRNA)可控制基因表达和调控。尽管ncRNA和TEs之间的关系是已知的,但获得测序基因组的有组织数据并非易事。在这项研究中,我们描述了PlaNC-TE(http://planc-te.cp.utfpr.edu.br),这是一个用户友好的门户网站,具有通过集成和分析植物ncRNA-TE数据创建的知识库。我们在40个植物基因组中鉴定出ncRNA和TE之间共有14 350个重叠。该数据库允许用户浏览,搜索和下载所有已分析的ncRNA和TE数据。全面的,PlaNC-TE不仅可以整理数据并提供有关ncRNA与植物中TE之间关系的见解,还有助于改善基因组注释策略。此外,这是第一个提供资源以广泛调查涉及植物中TE和ncRNA的功能和机制的数据库。
更新日期:2020-04-17
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