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The influence of age and osteoporosis on bone marrow stem cells from rats.
Bone & Joint Research ( IF 4.7 ) Pub Date : 2018-05-05 , DOI: 10.1302/2046-3758.74.bjr-2017-0302.r1 A Sanghani-Kerai 1 , L Osagie-Clouard 1 , G Blunn 1 , M Coathup 1
Bone & Joint Research ( IF 4.7 ) Pub Date : 2018-05-05 , DOI: 10.1302/2046-3758.74.bjr-2017-0302.r1 A Sanghani-Kerai 1 , L Osagie-Clouard 1 , G Blunn 1 , M Coathup 1
Affiliation
This study aimed to assess the effect of age and osteoporosis on the proliferative and differentiating capacity of bone-marrow-derived mesenchymal stem cells (MSCs) in female rats. We also discuss the role of these factors on expression and migration of cells along the C-X-C chemokine receptor type 4 (CXCR-4) / stromal derived factor 1 (SDF-1) axis.
中文翻译:
年龄和骨质疏松症对大鼠骨髓干细胞的影响。
本研究旨在评估年龄和骨质疏松症对雌性大鼠骨髓间充质干细胞 (MSCs) 增殖和分化能力的影响。我们还讨论了这些因子对沿 CXC 趋化因子受体 4 (CXCR-4) / 基质衍生因子 1 (SDF-1) 轴的细胞表达和迁移的作用。
更新日期:2020-08-21
中文翻译:
年龄和骨质疏松症对大鼠骨髓干细胞的影响。
本研究旨在评估年龄和骨质疏松症对雌性大鼠骨髓间充质干细胞 (MSCs) 增殖和分化能力的影响。我们还讨论了这些因子对沿 CXC 趋化因子受体 4 (CXCR-4) / 基质衍生因子 1 (SDF-1) 轴的细胞表达和迁移的作用。