The potentials of the magnetic resonance (MR) methods in the research of biomedical systems have been demonstrated during the 70 years of its existence. It is presented that the Cuban experience in quantitative magnetic resonance associated with molecular, preclinical and clinical studies of significant diseases and drugs development. MR “in vitro” and “in vivo” studies of sickle cell disease, the diabetic foot ulcer, the brain tumor response and the magnetic nano-particle pharmacokinetics, are presented as example. Furthermore, contributions and restrictions of magnetic resonance to diagnostic and optimization of therapeutic pathways are discussed in some concrete cases.

中文翻译：

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通过磁共振对复杂生物医学过程进行动力学研究：古巴经验

磁共振 (MR) 方法在生物医学系统研究中的潜力在其存在的 70 年中已得到证明。介绍了古巴在定量磁共振方面与重大疾病和药物开发的分子、临床前和临床研究相关的经验。以镰状细胞病、糖尿病足溃疡、脑肿瘤反应和磁性纳米颗粒药代动力学的 MR“体外”和“体内”研究为例。此外，还通过一些具体案例讨论了磁共振对诊断和治疗途径优化的贡献和限制。