Pine wilt disease, caused by the nematode Bursaphelenchus xylophilus, is one of the most devastating conifer diseases decimating several species of pine trees on a global scale. Here, we report the draft genome of Raoultella ornithinolytica MG, which is isolated from mountain-cultivated ginseng plant as an bacterial endophyte and shows nematicidal activity against B. xylophilus. Our analysis of R. ornithinolytica MG genome showed that it possesses many genes encoding potential nematicidal factors in addition to some secondary metabolite biosynthetic gene clusters that may contribute to the observed nematicidal activity of the strain. Furthermore, the genome was lacking key components of avermectin gene cluster, suggesting that nematicidal activity of the bacterium is not likely due to the famous anthelmintic agent of wide-spread use, avermectin. This genomic information of R. ornithinolytica will provide basis for identification and engineering of genes and their products toward control of pine wilt disease.

中文翻译：

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基因组学见解，细菌内生菌，解藻劳尔氏菌对松枯萎线虫的杀线虫活性。

由线虫Bursaphelenchus xylophilus引起的松树枯萎病是最具破坏性的针叶树病之一，在全球范围内毁灭了几种松树。在这里，我们报告了拟南芥拉尔特氏菌MG的基因组草图，该基因组是从山地人参植物中分离出的细菌内生菌，并显示出对B. xylophilus的杀线虫活性。我们对解鸟支菌的分析MG基因组显示，它除了具有一些次生代谢产物生物合成基因簇以外，还具有编码潜在杀线虫因子的许多基因，这些基因簇可能有助于菌株的杀线虫活性。此外，该基因组缺少阿维菌素基因簇的关键成分，这表明该细菌的杀线虫活性不太可能归因于著名的驱虫药阿维菌素。这个基因组信息R. ornithinolytica将为基因的鉴定和工程及其产品对松材线虫病的控制提供依据。