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Synthesis, Characterization, and Biological Evaluation of Unimetallic and Heterobimetallic Complexes of Bivalent Copper.
Bioinorganic Chemistry and Applications ( IF 4.7 ) Pub Date : 2018-04-12 , DOI: 10.1155/2018/2467463
Anshul Singh 1 , Ashu Chaudhary 1
Affiliation  

We present an inclusive characterization of the unimetallic and heterobimetallic complexes of copper synthesized using CuCl2 and diamine (4-fluoro 1,2-phenylenediamine) resulting in monometallic complex which further undergoes treatment with organometallic dichlorides of group 4 and 14 in 1 : 2 molar ratio resulting in heterobimetallic complexes. These complexes thoroughly characterized using various physical, analytical, and spectroscopic techniques indicate square planar and distorted octahedral geometry for the synthesized unimetallic and heterobimetallic complexes, respectively. These complexes were evaluated for their antimicrobial efficacy against various bacterial and fungal strains while hepatoprotective activity was also examined in male albino rats.

中文翻译:

二价铜的单金属和杂双金属配合物的合成,表征和生物学评价。

我们介绍了使用CuCl 2和二胺(4-氟1,2-苯二胺)合成的铜的单金属和杂双金属配合物的包容性表征,导致单金属配合物进一步在1:2摩尔中用4和14组的有机金属二氯化物进行处理产生异双金属配合物的比率。使用各种物理,分析和光谱技术对这些配合物进行了全面表征,分别表明了合成的单金属和异双金属配合物的正方形平面和扭曲的八面体几何形状。评估了这些复合物对各种细菌和真菌菌株的抗微生物功效,同时还在雄性白化病大鼠中检查了其肝保护活性。
更新日期:2018-04-12
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