Background: Parkinson’s disease (PD) motor symptoms can fluctuate and may not be accurately reflected during a clinical evaluation. In addition, access to movement disorder specialists is limited for many people with PD. The objective of this study was to assess the impact of motion sensor-based telehealth diagnostics on PD clinical care and management. Methods: Eighteen adults with PD were randomized to control or experimental groups. All participants were instructed to use a motion sensor-based monitoring system at home 1 day per week for 7 months. The system included a finger-worn motion sensor and tablet-based software interface that guided patients through tasks to quantify tremor, bradykinesia, and dyskinesia. Data were processed into motor symptom severity reports, which were reviewed by a movement disorder neurologist for the experimental group participants. After 3 months and 6 months, the control group participants visited the clinic for a routine appointment, while the experimental group participants had a videoconference or phone call instead. Results: Home-based assessments were completed with a median compliance of 95.7%. For a subset of participants, the neurologist successfully used information in the reports, such as quantified responses to treatment or progression over time, to make therapy adjustments. Changes in clinical characteristics from study start to end were not significantly different between the groups. Discussion: Individuals with PD were able and willing to use remote monitoring technology. Patient management aided by telehealth diagnostics provided comparable outcomes to standard care. Telehealth technologies combined with wearable sensors have the potential to improve care for disparate PD populations or those unable to travel.

中文翻译：

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使用可穿戴传感器对帕金森病进行远程医疗管理：一项探索性研究

背景：帕金森病 (PD) 运动症状可能会波动，并且在临床评估期间可能无法准确反映。此外，对于许多 PD 患者来说，接触运动障碍专家的机会有限。本研究的目的是评估基于运动传感器的远程医疗诊断对 PD 临床护理和管理的影响。方法：18 名患有 PD 的成年人被随机分配到对照组或实验组。指示所有参与者每周 1 天在家中使用基于运动传感器的监测系统，持续 7 个月。该系统包括一个手指佩戴的运动传感器和基于平板电脑的软件界面，可指导患者完成量化震颤、运动迟缓和运动障碍的任务。数据被处理成运动症状严重程度报告，由运动障碍神经科医生为实验组参与者进行审查。3 个月和 6 个月后，对照组参与者到诊所进行例行预约，而实验组参与者则改为视频会议或电话。结果：以家庭为基础的评估以 95.7% 的中位依从性完成。对于一部分参与者，神经学家成功地使用了报告中的信息，例如对治疗的量化反应或随时间的进展，以进行治疗调整。从研究开始到结束的临床特征变化在各组之间没有显着差异。讨论：患有 PD 的人能够并且愿意使用远程监控技术。由远程医疗诊断辅助的患者管理提供了与标准护理相当的结果。远程医疗技术与可穿戴传感器相结合，有可能改善对不同 PD 人群或无法旅行的人的护理。