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Pulmonary Mycobacterium Avium-Intracellulare Complex Infection in an Infant: A Silent and Coincidental Finding.
Pediatric Allergy, Immunology, and Pulmonology ( IF 0.9 ) Pub Date : 2017-12-28 , DOI: 10.1089/ped.2017.0766
Vishal Naik 1 , Pui-Ying Iroh Tam 1 , William Gershan 1 , Andrew A Colin 2 , Nadir Demirel 1
Affiliation  

An 11-month-old healthy infant girl was noted to have left lower lobe (LLL) opacities on chest X-ray (CXR) after developing desaturations during an elective cochlear implant surgery. Repeat CXR 10 days later revealed hyperexpansion of the left lung and persistent LLL opacity. Chest computerized tomography revealed enlarged mediastinal lymph nodes, left mainstem bronchial obstruction, and nodular opacities. Bronchoscopic biopsy of the endobronchial tissue revealed multiple necrotizing granulomas and grew Mycobacterium avium-intracellulare, Streptococcus viridans, and Actinomyces odontolyticus. This case illustrates the potential for significant mediastinal lymphadenopathy, and endobronchial and parenchymal lesions caused by nontuberculous mycobacteria, which can present insidiously and without respiratory symptoms in otherwise healthy infants, despite advanced pulmonary disease.

中文翻译:

婴儿肺分枝杆菌Avium-胞内复合物感染:沉默和偶然的发现。

注意到一名11个月大的健康女婴在择期人工耳蜗植入手术中出现不饱和现象后,在胸部X光片(CXR)上留下了左下叶(LLL)浑浊。10天后重复进行CXR,发现左肺过度扩张和持续性LLL不透明。胸部计算机断层扫描显示纵隔淋巴结肿大,左主干支气管阻塞和结节混浊。支气管内支气管镜的活检显示多发性坏死性肉芽肿,并生长了鸟分枝杆菌胞内,绿色链球菌和放线放线菌。这个案例说明了由非结核分枝杆菌引起的明显纵隔淋巴结肿大以及支气管内和实质病变的可能性,这些疾病在其他健康的婴儿中可能会隐匿且没有呼吸道症状,
更新日期:2019-11-01
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