We present a computational model of three-dimensional and unsteady hemodynamics within the primary large arteries in the human on 1,572,864 cores of the IBM Blue Gene/Q. Models of large regions of the circulatory system are needed to study the impact of local factors on global hemodynamics and to inform next generation drug delivery mechanisms. The HARVEY code successfully addresses key challenges that can hinder effective solution of image-based hemodynamics on contemporary supercomputers, such as limited memory capacity and bandwidth, flexible load balancing, and scalability. This work is the first demonstration of large fluid dynamics simulations of the aortofemoral region of the circulatory system at resolutions as small as 10 μm.

我们在 IBM Blue Gene/Q 的 1,572,864 个核心上提出了人体主大动脉内三维非稳态血流动力学的计算模型。需要循环系统大区域的模型来研究局部因素对整体血流动力学的影响，并为下一代药物输送机制提供信息。 HARVEY 代码成功解决了阻碍当代超级计算机上基于图像的血流动力学有效解决方案的关键挑战，例如有限的内存容量和带宽、灵活的负载平衡和可扩展性。这项工作首次以小至 10 μm 的分辨率演示了循环系统主动脉股区域的大型流体动力学模拟。