Background: RNA secondary structure is essential to understand the mechanism of RNAs. Method: In this paper, fledFold, a novel software for RNA secondary structure prediction, is introduced. It combines both thermodynamic and kinetic factors of RNA secondary structures and can predict RNA secondary structures from their primary sequences with local personal computers. Results: FledFold is implemented in C++ under Windows 7 and could run on windows 7 or later version with at least 2 GB of RAM. Fledfold is user friendly and could output results with multiple formats. Conslusion: FledFold will be a valuable tool for RNA researches and it could be downloaded freely from http://www.jlucomputer.com/fledfold.php

中文翻译：

---

FledFold：一种新的 RNA 二级结构预测软件

背景：RNA 二级结构对于理解 RNA 的机制至关重要。方法：本文介绍了一种新型的RNA二级结构预测软件fledFold。它结合了 RNA 二级结构的热力学和动力学因素，可以通过本地个人计算机从一级序列预测 RNA 二级结构。结果：FledFold 在 Windows 7 下用 C++ 实现，可以在至少 2 GB RAM 的 Windows 7 或更高版本上运行。Fledfold 是用户友好的，可以输出多种格式的结果。结论：FledFold 将成为 RNA 研究的宝贵工具，可从 http://www.jlucomputer.com/fledfold.php 免费下载